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3D FloTrix™ Serum-Free Medium for MSCs

Xeno-free, serum-free cell culture medium for isolation, expansion and large-scale production of MSCs.

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Overview

The 3D FloTrix™ MSC Serum-Free Medium is a pharmaceutical-grade, xeno-free platform designed to support scalable expansion of mesenchymal stem cells (MSCs). Utilising advanced 3D microcarrier systems, it enables efficient transition from 2D planar culture to 3D bioreactor while maintaining exceptional cell potency and characterisation. Backed by an active U.S. FDA Drug Master File, this platform provides the regulatory foundation and manufacturing excellence required for advanced therapeutic applications, positioning it at the forefront of modern cell therapy production.

Applications

● Industrial-Scale Cultivation of Multiple Mesenchymal Stem Cell Variants
● Advanced Therapeutic Medicinal Product (ATMP) Development
● cGMP-Compliant Industrial Bioprocessing

Product Features

● High specification with serum-free, animal origin-free, and phenol red-free formulation ensures minimal batch-to-batch variation.
● Ready-to-use convenience requiring no additional growth factors, coating, or surface treatment.
● Superior performance supporting large-scale expansion of various mesenchymal stem cell types.
● Extended culture capability enabling stable, continuous passaging for over 14 days.
● Dual culture flexibility compatible with both 2D and 3D culture modalities.
● Versatile application suitable for both primary cell isolation and subsequent passaging.
● Reliable supply chain with stable production capacity and ready-to-ship availability.
● Proven regulatory support through deep collaboration with pharmaceutical partners to accelerate drug approval.
● Quality assurance supported by GMP-compliant production with robust quality management systems.

Results

Cumulative Cell Expansion Fold in the

Scale-Up Process

Cumulative Cell Numbers Harvested in the Scale-Up Process

Cell Viability at Each Stage of Scale-Up

Cumulative Population Doubling Level (PDL) of Cells in the Scale-Up Process

Figure legend : Live/Dead staining of UC-MSCs cultured in 3D FloTrix™ MSC SFM versus comparator media at Day 4

Specification

Product Name	Specification	Storage
3D FloTrix MSC Serum-Free Basal Medium	500 mL/bottle	4 °C
3D FloTrix MSC Serum-Free Supplement	25 mL/bottle	-20 °C

coming soon

Brochurs

3D FloTrix™ MSC Serum Free Medium

coming soon

Apr 11,2025

Catalogue No./ Model	Product Name	Specification
RMZ112-PYJ	3D FloTrix MSC Serum-Free Basal Medium	500 mL/Bottle
RMZ112-B	3D FloTrix MSC Serum-Free Supplement	25 mL/Bottle
RMZ112-2D	3D FloTrix MSC Serum-Free Supplement (for 2D culture)	25 mL/Bottle