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3D TableTrix™ Microcarriers W01 (Tablets)

Porcine gelatin microcarriers for stem cells in proprietary dispersible tablet form, ideal for R&D.

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Overview

CytoNiche introduces the 3D TableTrix™ Gelatin Microcarrier W01 Tablets—a paradigm shift in scalable regenerative medicine. Representing the pinnacle of dose-controlled geometry, these tablets enable uniform microcarrier distribution across scales, creating an ideal biomimetic environment that supports exceptional cell viability and potency. Manufactured from pharmaceutical-grade biomimetic gelatin and supported by comprehensive regulatory documentation (including FDA DMF/MF and CDE filings), this platform delivers robust quality assurance from bench to bedside. More than a solution for current manufacturing needs, this technology is designed to establish a scalable global standard for next-generation cell therapy production.

Application

● Advanced Cell Therapies
● Gene Therapy Vector Production
● 3D Disease Modeling & Drug Discovery
● Bioprinting & Tissue Engineering

Product Features

● Precisely engineered tablet format ensuring consistent dosage and uniform dispersion.
● Regulatory certified with FDA-DMF/MF and CDE pharmaceutical excipient qualifications.
● Highly porous 3D structure providing highly-effective surface area to support high-density cell growth.
● Biomimetic elasticity buffers shear stress in dynamic bioreactor environments to preserve cell viability.
● Fully degradable through enzyme-free processes for gentle and efficient cell harvesting.
● Sterile and ready-to-use tablets that rapidly disperse upon hydration, requiring no pre-treatment.
● Broad compatibility with adherent cell types, including MSCs and fibroblasts.

Results

Up to 4 times more human diploid cells can be harvested from 3D TableTrix™ microcarriers as compared to traditional microcarriers, and the culture density can reach over 7 × 10⁶/mL.
Virus titer (tested by viral antigen amount) is nearly 3 times that of 2D process.

Continuous multi-stage scale-up subculture of MDCK cells in a Cell Culture System can be enabled with 3D TableTrix™ microcarrier, achieving peak cell density of 1 × 10⁷ /mL.
Hemagglutination titer of virus produced from MDCK cultured on 3D TableTrix™ microcarrier is nearly 4 times that of traditional spherical microcarriers.

Specification

Parameter	Specification
Structural Form	3D porous microsphere microcarrier, porosity >90%
Raw Material	Gelatin
Degradability	Fully degradable
Packaging	20 mg/tablet, 1 g/bottle; 6 g/10 g/20 g/bottle
Model	W01-6-6g ; W01-10-10g ; W01-20-20g ; W01-200
Sterility	Sterile
Microcarrier Particle Size (Dry)	100–200 µm
Pore Size Range (Swollen)	30–50 µm
Effective Growth Surface Area	9000 cm²/g
Applicable Cell Types	Various adherent cells (especially mesenchymal stem cells, fibroblasts)
Usage Method	Ready-to-use
Cell Harvesting	Microcarrier degradation process

Technical Data Sheet

Microcarrier	Material	Structure	Dissolvable	Bead Size (μm)	Surface Area （cm²/g）	Bead Number (particles/mg)	Pore Size (μm)	Packaging	Application Field
W01	Porcine Gelatin	Macroporous sphere	Yes	40-330	8300	4200	0-50	Sterile Tablets \| Sterile Powder in Closed System	Mesenchymal stromal cells and exosomes
V01	Bovine Gelatin	Macroporous sphere	Yes	140-480	7500	2200	30-50	Non-sterile power	Human and animal vaccines, i.e. Vero, MDCK, MRC5
G02	Bovine Gelatin	Macroporous sphere	Yes	110-380	5900	2400	30-50	Sterile Tablets \| Sterile Powder in Closed System	Lenti-virus, Adeno-associatedvirus, oncolytic virus, i.e. 293T cells
CW01	Recombinant Collagen	Macroporous sphere	Yes	120-300	6300	4300	20-40	Sterile Tablets \| Sterile Powder in Closed System	Mesenchymal stromal cells and exosomes

Brochures

Microcarrier

Centimeter-Scale Self-Assembling Tendon Organoids Drive Tissue Regeneration

Fang, T., Zhang, H., Xie, Y., Li, X., Liu, X., Wang, Z., Xue, Y., Xia, X., Wang, Z., Lei, T., Lin, R., Shen, W., Wu, B., Chen, Y., Du, Y., Chen, X., & Yin, Z. (2025). Centimeter‐Scale Self‐Assembling tendon organoids drive tissue regeneration. Advanced Science, 12(43), e09453.

Aug 29,2025