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3D TableTrix™ Microcarriers W01 (Tablets)

Porcine gelatin microcarriers for stem cells in proprietary dispersible tablet form, ideal for R&D.

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Overview

CytoNiche introduces the 3D TableTrix™ Gelatin Microcarrier W01 Tablets—a paradigm shift in scalable regenerative medicine. The pinnacle of dose-controlled geometry, these tablets guarantee uniform microcarrier distribution across all scales, forming an ideal biomimetic environment that supports extraordinary cell vitality and potency. Built from pharmaceutical-grade biomimetic gelatin and holding comprehensive FDA-DMF/MF and CDE regulatory certifications, this platform embodies absolute quality assurance from bench to bedside. It ensures seamless process integrity with ready-to-use dispersion and a unique, gentle enzyme-free harvest. This is the critical enabler, designed not just for today's processes, but to establish the scalable global standard for tomorrow's therapeutic breakthroughs.

Application

● Advanced Cell Therapies
● Gene Therapy Vector Production
● 3D Disease Modeling & Drug Discovery
● Bioprinting & Tissue Engineering

Product Features

● Precisely engineered tablet format ensuring consistent dosage and uniform dispersion.
● Regulatory certified with FDA-DMF/MF and CDE pharmaceutical excipient qualifications.
● Highly porous 3D structure providing highly-effective surface area to support high-density cell growth.
● Biomimetic elasticity buffers shear stress in dynamic bioreactor environments to preserve cell viability.
● Fully degradable through enzyme-free processes for gentle and efficient cell harvesting.
● Sterile and ready-to-use tablets that rapidly disperse upon hydration, requiring no pre-treatment.
● Broad compatibility with adherent cell types, including MSCs and fibroblasts.

Results

Up to 4 times more human diploid cells can be harvested from 3D TableTrix™ microcarriers as compared to traditional microcarriers, and the culture density can reach over 7 × 10⁶/mL.
Virus titer (tested by viral antigen amount) is nearly 3 times that of 2D process.

Continuous multi-stage scale-up subculture of MDCK cells in a Cell Culture System can be enabled with 3D TableTrix™ microcarrier, achieving peak cell density of 1 × 10⁷ /mL.
Hemagglutination titer of virus produced from MDCK cultured on 3D TableTrix™ microcarrier is nearly 4 times that of traditional spherical microcarriers.

Specification

Parameter	Specification
Structural Form	3D porous microsphere microcarrier, porosity >90%
Raw Material	Gelatin
Degradability	Fully degradable
Packaging	20 mg/tablet, 1 g/bottle; 6 g/10 g/20 g/bottle
Model	W01-6-6g ; W01-10-10g ; W01-20-20g ; W01-200
Sterility	Sterile
Microcarrier Particle Size (Dry)	100–200 µm
Pore Size Range (Swollen)	30–50 µm
Effective Growth Surface Area	9000 cm²/g
Applicable Cell Types	Various adherent cells (especially mesenchymal stem cells, fibroblasts)
Usage Method	Ready-to-use
Cell Harvesting	Microcarrier degradation process

Technical Data Sheet

Microcarrier	Material	Structure	Dissolvable	Bead Size (μm)	Surface Area （cm²/g）	Bead Number (particles/mg)	Pore Size (μm)	Packaging	Application Field
W01	Porcine Gelatin	Macroporous sphere	Yes	40-330	8300	4200	0-50	Sterile Tablets \| Sterile Powder in Closed System	Mesenchymal stromal cells and exosomes
V01	Bovine Gelatin	Macroporous sphere	Yes	140-480	7500	2200	30-50	Non-sterile power	Human and animal vaccines, i.e. Vero, MDCK, MRC5
G02	Bovine Gelatin	Macroporous sphere	Yes	110-380	5900	2400	30-50	Sterile Tablets \| Sterile Powder in Closed System	Lenti-virus, Adeno-associatedvirus, oncolytic virus, i.e. 293T cells
CW01	Recombinant Collagen	Macroporous sphere	Yes	120-300	6300	4300	20-40	Sterile Tablets \| Sterile Powder in Closed System	Mesenchymal stromal cells and exosomes