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3D FloTrix™ vivaVIAL Filling System

A purpose-built, automated vial filling platform for cell therapy manufacturing. This compact system integrates end-to-end processing—sorting, filling, stoppering, crimping, and in-line QC—with single-use tubing assemblies, delivering pharmaceutical-grade fill-weight accuracy (≤±0.1mL) at throughputs up to 1,000 vials/hour.

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Overview

The 3D FloTrix™ vivaFILL Filling System is a purpose-built

, automated platform meticulously engineered for precision in cell therapy manufacturing. This compact, high-performance system seamlessly integrates end-to-end processing—sorting, filling, stoppering, crimping, and in-line quality control—into a unified, closed system architecture utilizing single-use tubing assemblies. Coupled with the 3D FloTrix™ vivaMIX Intelligent Cell Mixing Module, the system leverages smart temperature-controlled mixing to preserve cell viability and achieve a perfectly homogenous suspension—safeguarding the consistency, quality, and integrity required in GMP-grade manufacturing.

Applications

● Advanced Therapy Medicinal Products (ATMPs)

● Master and Working Cell Bank (MCB/WCB) preparation
● Biologics & Complex Injectables

Product Features

● Pairs with our vivaMIX for temperature-controlled mixing that maintains cell viability and uniformity
● Vision-guided defect detection ensures precise fill consistency and operational reliability
● Integrated CleanCrimp Technology for hermetic sealing with built-in aluminium particulate containment
● High-Precision Filling System of volume accuracy ≤±0.1mL or ±5%
● Compact design with high-throughput operation for large-volume production of up to 1,000 vials/hour

Results

Filling volume accuracy for cell preparations: within ≤ ±0.1 mL or ±5%

Filling volume accuracy remains within ≤+0.1mL or +5% across varying fill volumes

Cell preparation filling density deviation with RSD≤10%

Post-filling viability deviation of the cell preparation is ≤5% from initia

Specification

Parameter	Specification
Min. Feed Volume	>50 mL
Filling Volume	0.1 - 10 mL
Throughput	Up to 1000 vials/hour
Accuracy	≤±0.1 mL or ±5%
Viability Loss	<5%
Compatibility	2/5/10 mL COP Vials Vented/Non-Vented Stoppers
Dimensions (L×W×H)	1263 × 651 × 700 mm
Weight	220 kg
Power Supply	AC 100-240 V, 50/60 Hz, 2300 W
USB Port	1
Ethernet Port	1×100 Mbit/s

3D FloTrix™ vivaVIAL Filling System

coming soon

Catalogue No./ Model	Product Name	Spec
vivaVIAL-00-01	3D FloTrix™ vivaFILL Filling System Controller	1 set
vivaVIAL-02-01	3D FloTrix™ vivaFILL Filling System Module A 2mL	1 set
vivaVIAL-05-01	3D FloTrix™ vivaFILL Filling System Module A 5mL	1 set
vivaVIAL-10-01	3D FloTrix™ vivaFILL Filling System Module A 10mL	1 set
VIAL-02-01	3D FloTrix™ vivaFILL Filling Tubing Kit 2mL	1 set
VIAL-05-01	3D FloTrix™ vivaFILL Filling Tubing Kit 5mL	1 set
VIAL-10-01	3D FloTrix™ vivaFILL Filling Tubing Kit 10mL	1 set

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