Products
3D Iintelligent" Manufacturing Platform for Cells
Products
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Products
3D RecomTrix® Recombinant Collagen Microcarriers
3D RecomTrix® Recombinant Collagen Microcarrier retains the major characteristics of the CytoNiche Microcarrier, with the only difference being that it is composed of non-animal sourced recombinant collagen protein.
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3D TableTrix® Microcarriers
The 3D TableTrix® microcarrier family is a series of independently developed products, consisting of tens of thousands of elastic three-dimensional porous microcarriers with a porosity >90%. The particle size is controllable within the range of 50-500 μm, with a large specific surface area. The uniformity is ≤100μm. It incorporates specific degradation technology, allowing gentle cell harvesting and forming a truly 3D biomimetic culture. The 3D TableTrix® microcarrier series (W series, V series, G series) complies with GMP-level production, suitable for adherent cell cultivation, and enables the harvesting of cells, viruses, and cell products. It has obtained two Chinese CDE (Center for Drug Evaluation) qualifications for pharmaceutical excipients (Record numbers: F20200000496; F20210000003), and three U.S. FDA qualifications for drug substances and pharmaceutical excipients (DMF II & IV types, MF II record numbers: 037798 & 035481, 29721).
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3D FloTrix® vivaFILL Cryovial Filling System
The 3D FloTrix® vivaFILL cell filling system effectively addresses risks in the formula-tion filling process, such as large filling volumes, challenging inter-batch quality control, and high costs. It enhances the accuracy, consistency, stability, and repeatability of cell products, meeting quality control requirements in the cell formulation production process for enterprises.
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3D FloTrix® vivaPACK Cryobag Filling System
3D FloTrix® vivaPACK Cryobag Filling System is a high-throughput automated filling equipment designed specifically for the production and preparation of cell therapy prod-ucts. Paired with closed sterile disposable tubing sets and cryopreservation bags, it can achieve various fully closed formulation filling processes with over a hundred bags.
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3D FloTrix® vivaSPIN Bioreactor
3D FloTrix® vivaSPIN Bioreactor is a closed, automated, and scalable stirred bioreactor developed by CytoNiche to achieve high-quality large-scale cultivation of 3D cells. Based on the core technology products, the 3D TableTrix® microcarrier, and the 3D FloTrix® dynamic cultivation process, CytoNiche has taken into full consideration factors such as fluid dynamics and process control parameters. The optimization design covers various aspects, including tank structure, pipe fittings, and control procedures.
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3D FloTrix® microSPIN 6-channel micro-bioreactor
3D FloTrix® microSPIN Multiplex System is an electrically driven magnetic stirring device designed to work in conjunction with the 3D Flo-Trix® 3D stirred cell culture plate. It enables the simultaneous exploration and validation of various process conditions, ensuring the maximization of cost reduction in research and development within a dynamic biomimetic environment. This device is suitable for research applications (uni-versities/hospitals), clinical applications (hospitals/testing companies), and research and development applications (pharmaceutical companies/CROs).
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3D FloTrix® miniSPIN FLEX System
3D FloTrix® miniSPIN FLEX System is an electrically driven magnetic stirring device designed specifically for the suspension culture of adherent cells. When combined with disposable reaction bottles, it facilitates scientific research, R&D exploration, and small-scale process validation. The device utilizes an ultralow-speed stirring mode to enhance the fluidity of the culture medium around the cells. It is suitable for the suspen-sion culture of adherent cells and microcarriers, single-cell suspension culture, strain and cell line screening, cell proliferation culture, and related process optimization.
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3D FloTrix® vivaPREP Cell Processing System
A fully closed and automated cell processing system, which leverages the principle of gradient centrifugation and integrates the practice of 3D FloTrix® 3D large-scale preparation of adherent cells, to achieve large-scale culture, separation, concentration, washing, and dispensing of adherent cells
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3D FloTrix® vivaPREP PLUS Cell Processing System
3D FloTrix® vivaPREP PLUS Cell Processing System,is a high-throughput, automated cell processing device designed specifically for the production of cell therapy products. When paired with a closed sterile disposable tubing set, it enables large-scale, closed-system processes such as washing and harvesting for various types of cells.
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3D FloTrix® vivaEXO Exosome Harvesting System
A fully enclosed and automated large-scale exosome processing system, which combines with the 3D FloTrix® 3D large-scale preparation practice of adherent cells, to achieve the large-scale preparation and production of exosome products
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3D FloTrix® vivaROCK Bioreactor Stystem
The 3D FloTrix® vivaROCK Bioreactor System is a disposable rocking bioreactor independently developed by CytoNiche. It provides assistance in achieving high-quality, scalable 3D cell cultivation, offering a new choice for research, process development, and manufacturing. Leveraging a unique agitation mode, the 3D FloTrix® vivaROCK Bioreactor System delivers excellent mixing performance, creating a low-shear, high-oxygen cell culture environment. Combined with the 3D FloTrix® vivaROCK cell culture bag, it forms a fully enclosed cultivation system, reducing the risk of contamination and enhancing the quality of cell cultivation.
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3D FloTrix® MSC Serum Free Medium
The 3D FloTrix® Mesenchymal Stem Cell Culture Medium is a serum-free and ani-mal-free medium for the proliferation and maintenance of mesenchymal stem cells. With high quality, cost-effectiveness, and safety assurance, it can help our pharmaceutical clients successfully go through drug application processes and expedite the develop-ment of biopharmaceuticals.
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3D ExoTrix Exosome
Exosome is a type of extracellular vesicle with a particle size of 30-150 nm. At present, it is mainly used in disease treatment, drug carrier, disease diagnosis, etc.
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Copyright: Beijing CytoNiche Biotechnology Co., Ltd.
Copyright: Beijing CytoNiche Biotechnology Co., Ltd.