3D FloTrix® vivaSPIN Bioreactor is a closed, automated, and scalable stirred bioreactor developed by CytoNiche to achieve high-quality large-scale cultivation of 3D cells. Based on the core technology products, the 3D TableTrix® microcarrier, and the 3D FloTrix® dynamic cultivation process, CytoNiche has taken into full consideration factors such as fluid dynamics and process control parameters. The optimization design covers various aspects, including tank structure, pipe fittings, and control procedures.